Latest

Scientists Develop Revolutionary DNA Repair Method To Stop Cell Death

Russian scientists have developed a breakthrough method of DNA repair which may prevent and cure diseases such as Alzheimer’s or Parkinson’s in the future. 

The new technique essentially stops the process of cell death.

Rt.com reports:

The research team led by Vasily M. Studitsky, professor at the Lomonosov Moscow State University,published their findings in an article “Structure of transcribed chromatin is a sensor of DNA damage” in the Science Advances journal.

“Early detection and repair of damaged DNA is essential for cell functioning and survival,” says the study.

The paper raises the question of single-strand breaks (SSBs) which are called in the research“common DNA damages generated during various processes of cell metabolism.”

“Unrepaired SSBs can interfere with transcription, replication, and DNA repair; induce accumulation of double-stranded DNA breaks; increase genomic instability and apoptosis [process of programmed cell death]; and lead to severe neurodegenerative diseases.” Alzheimer’s, Parkinson’s disease and spinal muscular atrophy are examples of such diseases.

Studitsky told science portal Psys.org that the team of scientists “has shown, not yet in the cell but in vitro, that the repair of breaks in the other DNA chain, which is ‘hidden’ in the nucleosome, is still possible.”

“According to our hypothesis, it occurs due to the formation of special small DNA loops in the nucleosome, although normally DNA wounds around the histone ‘spool’ very tightly,” he added.

As the DNA molecule is chemically unstable, its damage detection and repair are needed.

“These observations raise the possibility that nucleosomal structure could affect the process of detection and repair of DNA damages,” the study says.

The researchers added that their findings can suggest “the existence of a chromatin-specific, transcription-dependent mechanism that allows detection of NT-SSBs that are otherwise hidden in the chromatin structure.”

  • samson idemudia

    Hello everyone, i am very happy to share my testimony with you today. I am Samson Idemudia, based in New york city, USA i suffered from HIV for 6 years which i contacted from my ex, and i almost felt there was no hope for me. But God gave me a second chance. Just few months ago, i was browsing the internet when i came across a testimony of a Man that claimed he was cured from the same disease i had, it gave me a shock because i never heard from anyone there was a cure, right on the testimony he gave the Doctors name and contact, DR OGUNLEYE, and his email: dr.oguleye@gmail.com.
    I decided to contact the doctor, who then told me what to do to get his herbs, and how to take the dosage, after which i followed his instructions as i was told, Behold in three weeks i went to the hospital to get a test and i was negative. This is true and i need you too to give it a try because it worked for me and i also need people to hear about this Man, Doctor OGUNLEYE. Once again, here is his email : dr.oguleye@gmail.com